01

Clara for You

Voice AI-powered Mental Healthcare Navigation for Value-based Care

June 2025

Streamlining mental health evaluations and care delivery through AI technology

Call Clara Scan to call Clara
02

Untreated mental health conditions in patients are costly

$282B

Cost of untreated mental illness in the US each year

Yale

60%

Patients with depression are 60% more likely to develop type-2 diabetes than those without

Scientific Reports

3x

Patients with depression are 3x more likely to use emergency services

CMAJ

400%

ROI of treating anxiety and depression

WHO

The Challenge

Care teams lack the time to evaluate, diagnose, create and oversee intricate care plans for every patient in need.

03

The Solution is Clara

Clara is a voice AI clinical decision support tool and care navigator for mental health

🎯 Customizable

  • Tailoring to your specific needs
  • Integrates with existing EHR systems
  • Keeps providers at the center of care

πŸ”’ HIPAA Compliant

  • Secure technology to ensure patient and clinician confidence

πŸ•°οΈ Available 24/7

  • Automated screening and triage
  • Instant documentation
  • Seamless care coordination without additional staff

🩺 Evidence-based

  • Evidence-based clinical protocols
  • Physician-in-the-loop oversight
  • Automatically balances efficacy with cost

Solving Time and Cost Constraints

While mental health treatment improves outcomes and reduces costs, care teams are overwhelmed and often lack the time and resources to design and implement comprehensive care plans. Clara is the solution.

04

Clara manages all components of care delivery

From patient evaluation to care coordination

1

Referral

Patient inquiry or PCP referral

2

Evaluation

Clara conducts a ~20-minute structured phone screening using validated tools and protocols.

3

Care Plan Development

Clara drafts a personalized care plan for review.

4

Clinician Approval

Clinician signs off, and Clara initiates care coordination.

5

Care Delivery

Clara supports delivery of care per the approved plan. Care teams can be incorporated as-desired.

6

Follow-ups

Clara ensures continuous care through reminders and check-ins.

05

Risk-Based Care Stratification

Clara understands effective interventions differ by needs, and categorizes patients into appropriate urgency levels during the phone evaluation. Urgency levels and care pathways can be customized to your preferences and systems.

🟒
No Urgency
Not currently in need of support
Example: PHQ-9 score <5
  • Encourage healthy behaviors
  • Encourage use of support systems
  • Offer free resources if requested
  • Schedule for periodic check-in
🟑
Low Urgency
AI-guided support
Example: PHQ-9 score 5-9
  • AI-guided resource and activity discovery
  • AI-guided motivational interviewing, problem-solving therapy or behavioral activation
  • AI-guided CBT exercises and mindfulness
  • Potential for medication intervention if first-line efforts ineffective. Clara tracks progress and alerts clinician if re-evaluation is needed
  • Check-ins for progress tracking and new insights
🟠
Medium Urgency
Optimized clinician intervention
Example: PHQ-9 score 10-14
  • Potential for medication intervention, Clara recommends options factoring in polypharmacy considerations
  • All AI-based tools from low urgency situation used as initial treatment
  • Potential for defined number of therapy sessions. Clara handles clinician pairing and scheduling and reporting back to clinician
  • Psychiatry referal considered if first-line efforts ineffective. Clara handles clinician pairing, scheduling and reporting back to care team
  • Check-ins for progress tracking and new insights
πŸ”΄
High Urgency
Comprehensive clinician intervention
Example: PHQ-9 score 15+
  • Refer for full psychiatric evaluation, Clara handles clinician pairing, scheduling and reporting back to care team
  • Potential for defined number of therapy sessions, Clara handles clinician pairing, scheduling and reporting back to care team
  • Clara executes on psychiatrist recommended care plan

Treatment Philosophy

Patients may switch groups episodically. The goal is to move as many patients as possible from high and medium to low or no urgency groups through effective and customized treatment.

06

Benefits for You

Comprehensive mental health support without additional staffing or infrastructure costs

⚑ Operational Efficiency

  • 24/7 availability
  • Voice-based evaluation and care delivery
  • EHR integration for instant documentation
  • Lessen clinician burden without sacrificing care quality

🩺 Clinical Excellence

  • Expert-developed and responsive on-demand evaluations
  • Evidence-based interventions
  • Automated updates to care teams
  • Comprehensive care plans

πŸ’° Financial Savings

  • Reserve high cost interventions for most urgent cases
  • Prevent escalations between urgency groups
  • Increased medication and treatment adherence for comorbidities
  • Decrease ER visits and hospitalizations

πŸ‘₯ Patient Experience

  • Immediate 24/7 access without wait times
  • Voice-based care ideal for elderly populations
  • Automated and continuous care coordination for seamless experience
  • Customized experience from start to finish
  • Clara builds a memory of each patient, delivering personalized and accurate recommendations with every interaction
07

Our Team

You are is in good hands with Pythagoras AI's experienced leaders

Alexandra Stieglitz

Alexandra Stieglitz

Cofounder & Co-CEO (Leading strategy and partnerships)

Former founder and CEO of Pluma (now Skillsoft Coaching), a coaching software platform for new and emerging leaders. Enterprise clients included: Gilead, BioMarin, Dropbox, Adobe, Gap, Sephora, EY, Asurion, Uber and others. Sold to Skillsoft (NYSE:SKIL). MBA Harvard Business School. AB Princeton University.

Ajay Naik

Ajay Naik

Cofounder & Co-CEO (Leading technology and product)

Technology leader with almost two decades of experience building tech solutions with deep expertise in healthcare and AI. Focused on building scalable platforms that improve patient outcomes and clinical workflows. Previously led engineering teams at high-growth startups and established tech companies.

Our Advisors

We're supported by industry experts who guide our strategic vision and growth

Brain

Brian Kane

Healthcare Strategy & Growth Advisor

Brian A. Kane is recognized for his disciplined operating leadership, ability to lead large organizations, and deep financial expertise. He currently serves as a senior advisor to Welsh Carson and as Executive Chairman of Tivity Health. Previously, he was President of Aetna at CVS Health, where he played a key role in integrating Aetna into the broader CVS enterprise and strengthening operational and financial performance. From 2014 to 2021, he served as Chief Financial Officer of Humana, where he helped shape corporate strategy, led the company to exceed analysts’ expectations for 23 straight quarters, and oversaw its growing primary care business, now known as CenterWell Senior Primary Care. Before joining Humana, Mr. Kane spent 17 years at Goldman Sachs as a Managing Director in the Investment Banking Division, executing major financings, mergers and acquisitions, and managing shareholder relations across healthcare, consumer, financial, and hospitality sectors. He has also advised leading private equity firms on strategy, operations, and financial performance across a range of healthcare services companies.

Anisha

Anisha Patel-Dunn, D.O.

Healthcare Strategy Advisor

Anisha Patel-Dunn, D.O. served as Chief Medical Officer at LifeStance Health from 2019 to 2024. As CMO, Dr. Patel-Dunn was responsible for overseeing all clinical services delivered through LifeStance, ensuring that care quality met and exceeded professional standards. Prior to LifeStance, Dr. Patel-Dunn built and managed a large group practice, Pacific Coast Psychiatric Associates, now part of LifeStance Health. In addition to her executive work, Dr. Patel-Dunn has nearly 20 years of experience as a practicing board-certified adult psychiatrist.

Dr. Munasifi

Faisal A Munasifi, M.D.

Clinical Advisor

Dr. Munasifi has more than 40 years of experience practicing adult psychiatry. He has been in private practice in Tallahassee since 1982. He completed his internship and residency at the University of Miami where he also served as Medical Director in the Psychiatry Department. In addition to private practice, he has served as medical director at the Tallahassee Memorial HealthCare Behavioral Health Center and as a Clinical Associate Professor at the Florida State University College of Medicine. Dr. Munasifi is a Life Fellow of the American Psychiatric Association and is board certified by the American Board of Psychiatry and Neurology.

Kareem

Karim Lotfy, M.D.

Clinical Advisor

Dr. Lotfy has more than 15 years of experience practicing adult psychiatry. Dr. Lotfy is board certified in both Psychiatry and Addiction Medicine and licensed to practice in both Colorado and California. He completed his medical training at Cairo University, Egypt where he received outstanding honors. Dr. Lotfy completed his psychiatry training at Baylor College of Medicine in Houston, Texas where he was chief resident.